منابع مشابه
Genomes, Gould, and Emergence
The publication of the human genome has elicited commentary to the effect that since fewer genes were identified than anticipated, it follows that genes are less important to human biology than anticipated. The flaws in this syllogism are explained in the context of a treatise on how genomes operate and evolve and how genes function to produce embryos and brains. Most of our most cherished huma...
متن کاملMechanisms and Dynamics of Orphan Gene Emergence in Insect Genomes
Orphan genes are defined as genes that lack detectable similarity to genes in other species and therefore no clear signals of common descent (i.e., homology) can be inferred. Orphans are an enigmatic portion of the genome because their origin and function are mostly unknown and they typically make up 10% to 30% of all genes in a genome. Several case studies demonstrated that orphans can contrib...
متن کاملArt - Gould (J)
nature neuroscience • volume 2 no 3 • march 1999 The involvement of the hippocampal formation in learning has been recognized for decades1,2, but the cellular mechanisms underlying this association remain enigmatic. The hippocampal formation produces new neurons throughout adulthood in many vertebrates, from birds to primates3–8; however, although the number of neurons produced is high, the fun...
متن کاملThermodynamic Basis for the Emergence of Genomes during Prebiotic Evolution
The RNA world hypothesis views modern organisms as descendants of RNA molecules. The earliest RNA molecules must have been random sequences, from which the first genomes that coded for polymerase ribozymes emerged. The quasispecies theory by Eigen predicts the existence of an error threshold limiting genomic stability during such transitions, but does not address the spontaneity of changes. Fol...
متن کامل173-176 Gould
The methodology described in this article was developed to transcend the limitations of both approaches. Its goal is to use existing data to identify small areas with high levels of adolescent childbearing. The method is an active approach to identify what can be defined as “hot spots” for adolescent births, even when they are located in counties or communities where adolescent births are not c...
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ژورنال
عنوان ژورنال: Zygon®
سال: 2001
ISSN: 0591-2385,1467-9744
DOI: 10.1111/0591-2385.00369